OMIA:001249-9796 : Coat colour, brown, TYRP1-related in Equus caballus

In other species: cattle , dog , domestic cat , sheep , pig , golden hamster , North American deer mouse , goat , American mink , rabbit , Mongolian gerbil , American black bear

Categories: Pigmentation phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 612271 (trait) , 203290 (trait) , 115501 (gene)

Links to MONDO diseases: No links.

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal

Considered a defect: no

Key variant known: no

Key variant is published: no

Molecular basis: Rieder et al. (2001) reported two base substitutions in the horse TYRP1 gene, but neither was associated with a particular coat colour.


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2010 Li, B., He, XL., Zhao, YP., Wang, XJ., Manglai, D., Zhang, YR. :
[Molecular basis and applicability in equine color genetics]. Yi Chuan 32:1133-40, 2010. Pubmed reference: 21513164 .
2001 Rieder, S., Taourit, S., Mariat, D., Langlois, B., Guerin, G. :
Mutations in the agouti (ASIP), the extension (MC1R), and the brown (TYRP1) loci and their association to coat color phenotypes in horses (Equus caballus) Mammalian Genome 12:450-455, 2001. Pubmed reference: 11353392 . DOI: 10.1007/s003350020017.
1948 Castle, W.E. :
The Abc of Color Inheritance in Horses. Genetics 33:22-35, 1948. Pubmed reference: 17247268 .

Edit History

  • Created by Frank Nicholas on 12 Sep 2005
  • Changed by Frank Nicholas on 11 Sep 2011
  • Changed by Frank Nicholas on 09 Dec 2011
  • Changed by Frank Nicholas on 19 Sep 2012