OMIA:000202-10047 : Coat/skin colour, oculocutaneous albinism type I (OCA1), TYR-related in Meriones unguiculatus (Mongolian gerbil) |
In other species: Japanese medaka , axolotl , dark-spotted frog , Japanese wrinkled frog , Tufted capuchin , Rhesus monkey , hamadryas baboon , dog , red fox , domestic ferret , domestic cat , lion , humpback whale , ass (donkey) , pig , red deer , American bison , taurine cattle , rabbit , golden hamster , domestic guinea pig , Japanese ratsnake , ball python , water buffalo , four-striped grass mouse , ocelot gecko , American mink , Japanese raccoon dog , Rice frog
Categories: Pigmentation phene , Vision / eye phene
Links to possible relevant human trait(s) and/or gene(s) in OMIM: 203100 (trait) , 606952 (trait) , 606933 (gene)
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal recessive
Disease-related: no
Key variant known: yes
Year key variant first reported: 2016
Cross-species summary: Congenital lack of pigment in most parts of the body. Due to a non-functional form of the enzyme tyrosinase. Also known as oculocutaneous albinism (OCA), acromelanism and as the Himalayan coat-colour pattern
Associated gene:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| Tyr | Meriones unguiculatus | 14 | NC_083361.1 (73438551..73354290) | Tyr | Homologene, Ensembl , NCBI gene |
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2019). OMIA:000202-10047: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2016 | Ukaji, T., Iwasa, M.A., Kai, O. : |
| Tyrosinase (Tyr) gene mutation in albino Mongolian gerbil (Meriones unguiculatus) Open Journal of Animal Sciences 6(04):259-268, 2016. DOI: 10.4236/ojas.2016.64031. | |
| 1989 | Matsuzaki, T., Yasuda, Y., Nonaka, S. : |
| The Genetics of Coat Colors in the Mongolian Gerbil (Meriones- Unguiculatus) Jikken Dobutsu 38:337-41, 1989. Pubmed reference: 2806391. DOI: 10.1538/expanim1978.38.4_337. |
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- Created by Frank Nicholas on 06 May 2019