OMIA:001728-34903 : Sex determination in Trachemys scripta |
In other species: torafugu , Nile tilapia , sheep , northern pike , horse , ass , clearhead icefish , goldfish , ayu , Japanese quail , silver trevally , chicken , Mallard , common quail , turkey , swan goose , Canada goose , , taurine cattle , Gila monster , Chinese soft-shelled turtle , Atlantic salmon , whitespotted clarias
Categories: Reproductive system phene
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 261550 (trait) , 600956 (gene)
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: no
Species-specific description: Shen et al. (2023): "To determine the functional role of Cyp19a1 in turtle ovarian determination, we established loss- and gain-of function models through in ovo lentivirus-mediated genetic manipulation. ... our results suggest that Cyp19a1 is both necessary and sufficient for ovarian determination in the red-eared slider turtle, establishing causality and a direct genetic link between aromatase and reptilian sex determination and differentiation." This phene includes references to studies involving gene edited or genetically modified organisms (GMO).
Reference
2023 | Shen, J., Sun, W., Wu, K., Zhuang, T., Lei, J., Ma, Q., Xiao, L., Ge, C. : |
Loss- and gain-of-function analyses reveal the essential role of Cyp19a1 in ovarian determination of the red-eared slider turtle. Genetics :, 2023. Pubmed reference: 36947451 . DOI: 10.1093/genetics/iyad041. |
Edit History
- Changed by Imke Tammen2 on 25 Mar 2023
- Created by Imke Tammen2 on 25 Mar 2023