OMIA:001728-34903 : Sex determination in Trachemys scripta

In other species: torafugu , Nile tilapia , sheep , northern pike , horse , ass , clearhead icefish , goldfish , ayu , Japanese quail , silver trevally , chicken , Mallard , common quail , turkey , swan goose , Canada goose , , taurine cattle , Gila monster , Chinese soft-shelled turtle , Atlantic salmon , whitespotted clarias

Categories: Reproductive system phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 261550 (trait) , 600956 (gene)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: no

Species-specific description: Shen et al. (2023): "To determine the functional role of Cyp19a1 in turtle ovarian determination, we established loss- and gain-of function models through in ovo lentivirus-mediated genetic manipulation. ... our results suggest that Cyp19a1 is both necessary and sufficient for ovarian determination in the red-eared slider turtle, establishing causality and a direct genetic link between aromatase and reptilian sex determination and differentiation." This phene includes references to studies involving gene edited or genetically modified organisms (GMO).


2023 Shen, J., Sun, W., Wu, K., Zhuang, T., Lei, J., Ma, Q., Xiao, L., Ge, C. :
Loss- and gain-of-function analyses reveal the essential role of Cyp19a1 in ovarian determination of the red-eared slider turtle. Genetics :, 2023. Pubmed reference: 36947451 . DOI: 10.1093/genetics/iyad041.

Edit History

  • Changed by Imke Tammen2 on 25 Mar 2023
  • Created by Imke Tammen2 on 25 Mar 2023