OMIA:002637-9940 : Adaptation, environment, generic in Ovis aries

In other species: pike icefish , turbot , chicken , goat , Bactrian camel , pig , Wuchang bream , white-tailed jackrabbit , snowshoe hare , taurine cattle , woolly mammoth , , Atlantic cod , muskox , reindeer , Steller's sea cow , hamadryas baboon

Categories: Normal phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: no

Mapping: Cheng et al. (2023) analysed “whole-genome sequencing individuals of 1,098 domestic sheep from 154 breeds, and 69 wild sheep from seven Ovis species. … … several introgressed haplotypes contributed to the morphological differentiations across sheep breeds … .Our results reveal that introgression events from wild Ovis species contributed to the high rate of morphological differentiation in sheep breeds, but also to individual variation within breeds. We propose that long divergent haplotypes are a ubiquitous source of phenotypic variation that allows adaptation to a variable environment, and that these remain intact in the receiving population probably due to reduced recombination.”


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Ceccobelli, S., Landi, V., Senczuk, G., Mastrangelo, S., Sardina, M.T., Ben-Jemaa, S., Persichilli, C., Karsli, T., Bâlteanu, V.A., Raschia, M.A., Poli, M.A., Ciappesoni, G., Muchadeyi, F.C., Dzomba, E.F., Kunene, N.W., Lühken, G., Deniskova, T.E., Dotsev, A.V., Zinovieva, N.A., Zsolnai, A., Anton, I., Kusza, S., Carolino, N., Santos-Silva, F., Kawęcka, A., Świątek, M., Niżnikowski, R., Špehar, M., Anaya, G., Granero, A., Perloiro, T., Cardoso, P., Grande, S., de Los Santos, B.L., Danchin-Burge, C., Pasquini, M., Martínez Martínez, A., Delgado Bermejo, J.V., Lasagna, E., Ciani, E., Sarti, F.M., Pilla, F. :
A comprehensive analysis of the genetic diversity and environmental adaptability in worldwide Merino and Merino-derived sheep breeds. Genet Sel Evol 55:24, 2023. Pubmed reference: 37013467 . DOI: 10.1186/s12711-023-00797-z.
Cheng, H., Zhang, Z., Wen, J., Lenstra, J.A., Heller, R., Cai, Y., Guo, Y., Li, M., Li, R., Li, W., He, S., Wang, J., Shao, J., Song, Y., Zhang, L., Billah, M., Wang, X., Liu, M., Jiang, Y. :
Long divergent haplotypes introgressed from wild sheep are associated with distinct morphological and adaptive characteristics in domestic sheep. PLoS Genet 19:e1010615, 2023. Pubmed reference: 36821549 . DOI: 10.1371/journal.pgen.1010615.

Edit History

  • Changed by Imke Tammen2 on 25 Feb 2023
  • Created by Imke Tammen2 on 25 Feb 2023