OMIA 000201-9796 : Coat colour, agouti in Equus caballus |
Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
---|---|---|---|---|---|---|
ASIP | agouti signaling protein | Equus caballus | 22 | NC_009165.3 (26009341..26072655) | ASIP | Homologene, Ensembl, NCBI gene |
Variants
By default, variants are sorted chronologically by year of publication, to provide a historical perspective. Readers can re-sort on any column by clicking on the column header. Click it again to sort in a descending order. To create a multiple-field sort, hold down Shift while clicking on the second, third etc relevant column headers.
WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
Since October 2021, OMIA includes a semiautomated lift-over pipeline to facilitate updates of genomic positions to a recent reference genome position. These changes to genomic positions are not always reflected in the ‘acknowledgements’ or ‘verbal description’ fields in this table.
OMIA Variant ID | Breed(s) | Variant Phenotype | Gene | Allele | Type of Variant | Source of Genetic Variant | Reference Sequence | Chr. | g. or m. | c. or n. | p. | Verbal Description | EVA ID | Inferred EVA rsID | Year Published | PubMed ID(s) | Acknowledgements |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
509 | Coat colour, recessive black | ASIP | a | deletion, small (<=20) | Naturally occurring variant | 22 | g.2174_2184del | c.191_201del | 2001 | 11353392 |
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2021 | Cieslak, J., Brooks, S.A., Wodas, L., Mantaj, W., Borowska, A., Sliwowska, J.H., Ziarniak, K., Mackowski, M. : | |
Genetic background of the Polish primitive horse (Konik) coat color variation-new insight into dun dilution phenotypic effect. J Hered 112:436-442, 2021. Pubmed reference: 34432873. DOI: 10.1093/jhered/esab034. | ||
2020 | Corbin, L.J., Pope, J., Sanson, J., Antczak, D.F., Miller, D., Sadeghi, R., Brooks, S.A. : | |
An Independent Locus Upstream of <i>ASIP</i> Controls Variation in the Shade of the Bay Coat Colour in Horses. Genes (Basel) 11:, 2020. Pubmed reference: 32486210. DOI: 10.3390/genes11060606. | ||
Nguyen, T.B., Paul, R.C., Okuda, Y., LE, T.N.A., Pham, P.T.K., Kaissar, K.J., Kazhmurat, A., Bibigul, S., Bakhtin, M., Kazymbet, P., Maratbek, S.Z., Meldebekov, A., Nishibori, M., Ibi, T., Tsuji, T., Kunieda, T. : | ||
Genetic characterization of Kushum horses in Kazakhstan based on haplotypes of mtDNA and Y chromosome, and genes associated with important traits of the horses. J Equine Sci 31:35-43, 2020. Pubmed reference: 33061782. DOI: 10.1294/jes.31.35. | ||
2019 | Mackowski, M., Wodas, L., Brooks, S.A., Cieslak, J. : | |
TBX3 and ASIP genotypes reveal discrepancies in officially recorded coat colors of Hucul horses. Animal :1-6, 2019. Pubmed reference: 30614426. DOI: 10.1017/S1751731118003506. | ||
Shang, S., Yu, Y., Dang, W., Zhao, Y., Zhang, J., Qin, X., Irwin, D.M., Wang, Q., Liu, F., Wang, Z., Zhang, S., Wang, Z. : | ||
Synergy between MC1R and ASIP for coat color in horses (Equus caballus). J Anim Sci :, 2019. Pubmed reference: 30785190. DOI: 10.1093/jas/skz071. | ||
2016 | Jacobs, L.N., Staiger, E.A., Albright, J.D., Brooks, S.A. : | |
The MC1R and ASIP coat color loci may impact behavior in the horse. J Hered 107:214-9, 2016. Pubmed reference: 26884605. DOI: 10.1093/jhered/esw007. | ||
Reissmann, M., Musa, L., Zakizadeh, S., Ludwig, A. : | ||
Distribution of coat-color-associated alleles in the domestic horse population and Przewalski's horse. J Appl Genet 57:519-525, 2016. Pubmed reference: 27194311. DOI: 10.1007/s13353-016-0352-7. | ||
2013 | Teixeira, R.B., Rendahl, A.K., Anderson, S.M., Mickelson, J.R., Sigler, D., Buchanan, B.R., Coleman, R.J., McCue, M.E. : | |
Coat color genotypes and risk and severity of melanoma in gray Quarter horses. J Vet Intern Med 27:1201-8, 2013. Pubmed reference: 23875712. DOI: 10.1111/jvim.12133. | ||
2010 | Bellone, RR. : | |
Pleiotropic effects of pigmentation genes in horses. Anim Genet 41 Suppl 2:100-10, 2010. Pubmed reference: 21070283. DOI: 10.1111/j.1365-2052.2010.02116.x. | ||
Li, B., He, XL., Zhao, YP., Wang, XJ., Manglai, D., Zhang, YR. : | ||
[Molecular basis and applicability in equine color genetics]. Yi Chuan 32:1133-40, 2010. Pubmed reference: 21513164. | ||
2009 | Kakoi, H., Tozaki, T., Nagata, S., Gawahara, H., Kijima-Suda, I. : | |
Development of a method for simultaneously genotyping multiple horse coat colour loci and genetic investigation of basic colour variation in Thoroughbred and Misaki horses in Japan. J Anim Breed Genet 126:425-31, 2009. Pubmed reference: 19912416. DOI: 10.1111/j.1439-0388.2009.00841.x. | ||
Lewin, H.A. : | ||
Genetics. It's a bull's market. Science 324:478-9, 2009. Pubmed reference: 19390037. DOI: 10.1126/science.1173880. | ||
Ludwig, A., Pruvost, M., Reissmann, M., Benecke, N., Brockmann, G.A., Castaños, P., Cieslak, M., Lippold, S., Llorente, L., Malaspinas, A.S., Slatkin, M., Hofreiter, M. : | ||
Coat color variation at the beginning of horse domestication. Science 324:485, 2009. Pubmed reference: 19390039. DOI: 10.1126/science.1172750. | ||
Rieder, S. : | ||
Molecular tests for coat colours in horses. J Anim Breed Genet 126:415-24, 2009. Pubmed reference: 19912415. DOI: 10.1111/j.1439-0388.2009.00832.x. | ||
2008 | Royo, L.J., Fernández, I., Azor, P.J., Alvarez, I., Pérez-Pardal, L., Goyache, F. : | |
Technical note: a novel method for routine genotyping of horse coat color gene polymorphisms. J Anim Sci 86:1291-5, 2008. Pubmed reference: 18310485. DOI: 10.2527/jas.2007-0498. | ||
2002 | Henner, J., Poncet, P.A., Aebi, L., Hagger, C., Stranzinger, G., Rieder, S. : | |
Horse breeding: genetic tests for the coat colors chestnut, bay and black. Results from a first study in the Swiss Franches-Montagnes horse breed. 144:405-412, 2002. Pubmed reference: 12224446. | ||
2001 | Rieder, S., Taourit, S., Mariat, D., Langlois, B., Guerin, G. : | |
Mutations in the agouti (ASIP), the extension (MC1R), and the brown (TYRP1) loci and their association to coat color phenotypes in horses (Equus caballus) Mammalian Genome 12:450-455, 2001. Pubmed reference: 11353392. DOI: 10.1007/s003350020017. | ||
1948 | Castle, W.E. : | |
The Abc of Color Inheritance in Horses. Genetics 33:22-35, 1948. Pubmed reference: 17247268. |
Edit History
- Created by Frank Nicholas on 12 Sep 2010
- Changed by Frank Nicholas on 11 Sep 2011
- Changed by Frank Nicholas on 09 Dec 2011
- Changed by Frank Nicholas on 18 Sep 2012
- Changed by Frank Nicholas on 19 Sep 2012